Study of the Relation between Aging and Pesticides: A Review

Renata Cristina-Pereira

Laboratory of Biomathematics and Physical Anthropology, Post-graduation Program of Environment Sciences, Alfenas, Minas Gerais State, Brazil.

Anna Luiza de Araújo Ribeiro

Laboratory of Biomathematics and Physical Anthropology, School of Medicine, Alfenas, Minas Gerais State, Brazil.

Anna Cláudia Ferreira Nunes

Laboratory of Biomathematics and Physical Anthropology, School of Medicine, Alfenas, Minas Gerais State, Brazil.

Luca Casale Guereschi

Laboratory of Biomathematics and Physical Anthropology, School of Medicine, Alfenas, Minas Gerais State, Brazil.

Maria Amália Garcia da Silveira Araújo

Laboratory of Biomathematics and Physical Anthropology, School of Medicine, Alfenas, Minas Gerais State, Brazil.

Maria Tereza Gonçalves-Mendes

Laboratory of Biomathematics and Physical Anthropology, Post-graduation Program of Environment Sciences, Alfenas, Minas Gerais State, Brazil and Laboratory of Biomathematics and Physical Anthropology, School of Medicine, Alfenas, Minas Gerais State, Brazil.

Kaynara Trevisan

Laboratory of Biomathematics and Physical Anthropology, Post-graduation Program of Environment Sciences, Alfenas, Minas Gerais State, Brazil.

Heberson Teixeira da Silva

Laboratory of Biomathematics and Physical Anthropology, Post-graduation Program of Environment Sciences, Alfenas, Minas Gerais State, Brazil.

Tales Alexandre Aversi-Ferreira *

Laboratory of Biomathematics and Physical Anthropology, Post-graduation Program of Environment Sciences, Alfenas, Minas Gerais State, Brazil.

*Author to whom correspondence should be addressed.


Aims: The main aim of this study was to use specific data from the literature on ageing, correlating this with the pesticide contamination, in order to understand the relationship with an increasingly ageing population.

Study Design: A systematic review was performed.

Place and Duration of Study: Laboratory of Biomathematics of the Federal University of Alfenas, Minas Gerais State, Brazil, between April 2023 and August 2023.

Methodology: A systematic search of articles was performed using the CAPES Periodic platform, a searcher from the Education Ministry of Brazil that contains Web of Science, Scopus, MedLine, from August 2020 to May 2023. For this review, the subject’s “aging theory”; “neuroscience and pathologies to aging”; “aging and aging-associated changes”; “pesticides and pesticide toxicity”; “pesticide toxicity and neurotoxicity”; “longevity and healthy aging”; “aging human and pesticides” were searched together using the type of material “articles” in English language. Some articles about “population growth”; “world population”; “population-aging” were used for epistemological composition of this work content subjects.

Results: From the 19.720 articles after the exclusion and the inclusion criteria made with the subjects most pertinent to the objectives of this work; 19.570 articles were excluded, remaining 150 ones, of which 116 were qualitative in scope and 34 quantitative.

Conclusion: The complex relationship between the pesticide contamination and the condition of the exposed individual may be associated with premature ageing and a greater susceptibility to debilitating age-related diseases. Although technology is increasingly improved in its innovations, health and environmental regulations have not been able to rid the production processes of their potential to pollute the environment and cause health problems for those exposed to them.

Keywords: Aging theory, precocious aging, pesticide, free radicals, oxidative stress, epigenome

How to Cite

Cristina-Pereira, R., Ribeiro, A. L. de A., Nunes, A. C. F., Guereschi, L. C., Araújo, M. A. G. da S., Gonçalves-Mendes, M. T., Trevisan, K., Silva, H. T. da, & Aversi-Ferreira, T. A. (2024). Study of the Relation between Aging and Pesticides: A Review. International Neuropsychiatric Disease Journal, 21(4), 26–46.


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