Magnetic Resonance Imaging (MRI) Insights into Brain Morphology and Connectivity Disruptions in Schizophrenia

Samiksha Joshi

J J Hospital, J J Marg, Nagpada-Mumbai Central, Off Jijabhoy Road, Mumbai, Maharashtra, India.

Mohit Kumar Pandey

Medical Imaging Technology, Department of Radio-diagnosis, Goa Medical College, Goa, India.

Bhawna Solanki *

Medical Imaging Technology, Department of Radio-diagnosis, Goa Medical College, Goa, India.

Pushpendra Kumar Rajput

Department of Paramedical Sciences Subharti Medical College, Swami Vivekanand Subharti University Meerut, India.

Mame Shalini Singh

NPS Department Mangalayatan University, Beswan Aligarh, India.

Hina Praveen

Gautham College Affiliated to RGUHS, Bangalore, India.

Manthan Gurav

J J Hospital, J J Marg, Nagpada-Mumbai Central, Off Jijabhoy Road, Mumbai, Maharashtra, India.

*Author to whom correspondence should be addressed.


Abstract

This review explores the transformative impact of Magnetic Resonance Imaging (MRI) on understanding schizophrenia. Structural MRI has unveiled significant alterations in brain regions like the hippocampus and prefrontal cortex, offering detailed insights into anatomical irregularities. Functional MRI studies have shed light on disruptions within the default mode network, providing valuable insights into cognitive deficits associated with the disorder. Additionally, Diffusion Tensor Imaging has highlighted white matter abnormalities, underscoring compromised interregional communication within the brain. Despite persistent challenges such as population heterogeneity and variations in imaging protocols, MRI techniques have significantly advanced our understanding of schizophrenia's neurobiological aspects.

Keywords: Artificial intelligence, brain morphology, cognitive deficits, connectivity disruptions, magnetic resonance imaging, schizophrenia, neurobiological aspects


How to Cite

Joshi, Samiksha, Mohit Kumar Pandey, Bhawna Solanki, Pushpendra Kumar Rajput, Mame Shalini Singh, Hina Praveen, and Manthan Gurav. 2024. “Magnetic Resonance Imaging (MRI) Insights into Brain Morphology and Connectivity Disruptions in Schizophrenia”. International Neuropsychiatric Disease Journal 21 (3):6-10. https://doi.org/10.9734/indj/2024/v21i3431.

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