Diabetes in the Context of Stroke (Local Study)
International Neuropsychiatric Disease Journal,
Background: Cerebrovascular diseases (CVD), including stroke, are considered as a high burden heath issue around the world. Diabetes is a well-established risk factor for stroke that affects both severity and outcome.
Objectives: The objective of this study is to evaluate cerebral stroke in diabetic patients and the impact of diabetes mellitus on the severity and outcome of all types of strokes.
Patients and Methods: This study included 500 patients with the first attack stroke who were classified into two groups; Group A: 404 diabetic patients & Group B: 96 non-diabetic patients. All patients were diagnosed clinically and with base line CT (Computed Tomography) brain and stroke severity was evaluated by NIHSS within 24 hours of admission.
Results: The mean NIHSS in the diabetic cases was 10.35 ± 2.51 which was statistically significant higher as compared with the non-diabetic cases (7.25 ± 1.02) (P <0.001). The percentage of cases with infarction stroke was higher in the diabetic group, however it did not detect major dissimilarity between the 2 groups.
Conclusion: Cardiovascular complications including cerebral strokes occur in higher rates in diabetic patients as compared with the non-diabetic. The outcomes of cerebral strokes were worse as compared with the non-diabetic.
- cardiovascular complications
How to Cite
Echouffo-Tcheugui JB, Xu H, Matsouaka RA, et al. Diabetes and long-term outcomes of ischaemic stroke: findings from Get with the Guidelines-Stroke. European heart Journal. 2018;39(25): 2376-2386.
O'donnell MJ, Xavier D, Liu L, et al. Risk factors for ischaemic and intracerebral haemorrhagic stroke in 22 countries (the INTERSTROKE study): a case-control study." The Lancet. 2010;376(9735):112-123.
Sarwar N, Gao P, Seshasai S, et al. Emerging Risk Factors Collaboration Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: A collaborative meta-analysis of 102 prospective studies. Lancet. 2010;375(9733):2215-2222.
Karapanayiotides T, Piechowski-Jozwiak B, Van Melle G, et al. Stroke patterns, etiology, and prognosis in patients with diabetes mellitus." Neurology. 2004;62(9):1558-1562.
Tun NN, Arunagirinathan G, Munshi SK. Diabetes mellitus and stroke: a clinical update." World journal of diabetes. 2017;8(6):235.
Bloomfield GS, Wang TY, Boulware, et al. Implementation of management strategies for diabetes and hypertension: from local to global health in cardiovascular diseases." Global heart. 2015;10(1):31-38.
Boehme AK, Esenwa C, Elkind MS. Stroke risk factors, genetics, and prevention." Circulation Research. 2017;20(3):472- 495.
Kumar GS, Rajeswaran S, Padmanaban U. Study comparing the clinical profile of patients with stroke in diabetic and non-diabetic patients. International Journal of Advances in Medicine. 2019;6(5):1397.
Subhash A, Kumar CR, Singh NK, et al. Stroke in patients with and without diabetes mellitus." Journal of Clinical and Scientific Research. 2018;7(1):7.
Altemimi MT, Hashim AR. Acute Stroke in Diabetes Mellitus: A Prospective Observational Study Evaluating the Course and Short-Term Outcome in Basrah, Southern Iraq." Cureus. 2019;11(10).
Patibandla S, Appikatla T, Jayasingh K. Study of the severity of stroke at the time of presentation in diabetic patients correlating with glycemic control." Int J Adv Med. 2017;4(02):396-400.
Ahmed Al-Weshahy, Rania El-Sherif, Khaled Abd Al-Wahhab Selim, Ayman Heikal. Short term outcome of patients with hyperglycemia and acute stroke; 2017.
Gedawy A, Martinez J, Al‐Salami H, et al. Oral insulin delivery: existing barriers and current counter‐strategies." Journal of pharmacy and pharmacology. 2018;70(2):197-213.
Heidenreich PA, Trogdon JG, Khavjou OA, et al. Forecasting the future of cardiovascular disease in the United States: a policy statement from the American Heart Association. Circulation. 2011;123(8):933-944.
Putaala J, Liebkind R, Gordin D, et al. Diabetes mellitus and ischemic stroke in the young: clinical features and long-term prognosis." Neurology. 2011;76(21):1831-1837.
Kamalesh M, Shen J, Eckert GJ. Long term postischemic stroke mortality in diabetes: a veteran cohort analysis." Stroke. 2008;39(10):2727-2731.
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