Knowledge and Attitudes of Caregivers’ of People with Schizophrenia towards the Illness: A Cross-Sectional Study from a Regional Psychiatric Hospital in Nigeria

Main Article Content

E. A. Uteh Blessing
O. Olotu Sunday
O. Omoaregba Joyce
O. James Bawo


Aim: To ascertain the attitudes of caregivers of patients with schizophrenia comprising their knowledge of the illness and social distance towards people with the illness.

Study Design: A cross sectional study design.

Place and Duration of Study: Federal Neuropsychiatric Hospital, Edo State, Nigeria, between April and July 2015.

Methodology: A systematic random sample of caregiver/patient dyads (n=281) were recruited. Caregivers were administered a socio-demographic questionnaire and, a brief interview on their knowledge of the aetiological factors, treatment for schizophrenia and level of social distance towards people with schizophrenia. Patients were administered a socio-demographic questionnaire and the PANSS.

Results: Three hundred and forty-one caregivers were approached but 281 gave consent and participated in the study (response rate was 82%, level of significance value was set at p<0.05 and 95% confidence interval was used). Among the 281 caregivers surveyed, 22.7% mostly ascribed psychosocial cause for schizophrenia, their level of knowledge of schizophrenia was generally average (49.5%). More than two-thirds of the caregivers reported high social distancing. Better attitudes to schizophrenia among caregivers was significantly associated with caregivers who were unemployed (p<0.03) and caregivers whose patients’ had at least 12 years of formal education (p<0.01).

Conclusion: Average knowledge of disease aetiology among caregivers was associated with high social distancing. Qualitative studies are required to explore the interactions of these identified factors.

Caregivers, schizophrenia, knowledge, attitudes.

Article Details

How to Cite
Blessing, E. A. U., Sunday, O. O., Joyce, O. O., & Bawo, O. J. (2020). Knowledge and Attitudes of Caregivers’ of People with Schizophrenia towards the Illness: A Cross-Sectional Study from a Regional Psychiatric Hospital in Nigeria. International Neuropsychiatric Disease Journal, 14(4), 59-70.
Original Research Article


World Health Organization. The Global burden of diseases: 2004 Update. Geneva, Switzerland: WHO Press; 2008.

Oheari JU. Caregiver burden and psychotic patients’ perception of social support in a Nigerian setting. Soc. Psychiatry Psychiatr. Epidemiol. 2001;36: 86–93.

Fiorillo A, Bassi M, de Girolamo G, Catapano F, Romeo F. The impact of a psychoeducational intervention on family members’ views about schizophrenia: Results from the OASIS Italian multi-centre study. Int. J. Soc. Psychiatry. 2011;57:596–603.

Shinde M, Desai A, Pawar S. Knowledge, attitudes and practices among caregivers of patients with schizophrenia in Western Maharashtra. Int. J. Sci. Res. 2014;3:516–522.

Neupane D, Dhakal S, Thapa S, Bhandari PM. Caregivers’ attitude towards people with mental illness and perceived stigma: A cross- sectional study in a tertiary hospital in Nepal. PLoS One. 2016;1–12.

Teferra S, Hanlon C, Beyero T, Jacobsson L, Shibre T. Perspectives on reasons for non-adherence to medication in persons with schizophrenia in Ethiopia: A qualitative study of patients, caregivers and health workers. BMC Psychiatry. 2013;13:1.

Omolayo BO, Olawa DB. Attitude of care-givers towards mental illness, social support and coping strategy as predictors of relapse among mental patients. 2013;2: 89–98.

Adewuya AO, MR. Social distance towards people with mental illness amongst Nigerian 10.1007/s00127-005-, university students. Soc Psychiatry Psychiatr Epidemiol. 2005;40:865–868.

Gureje O, Lasebikan VO, Ephraim-Oluwanuga O, Olley BO, Kola L. Community study of knowledge of and attitude to mental illness in Nigeria. Br. J. Psychiatry. 2005;186:436–441.

Igberase O, Okogbeni E. Beliefs about the cause of schizophrenia among caregivers in Midwestern Nigeria. Ment. Illn. 2017;9.

Adewuya A, Makanjuola R. Ay beliefs regarding causes of mental illness in Nigeria: Pattern and correlates. Soc Psychiatry Psychiatr Epidemiol. 2008;43: 336–41.

WHO. The World Health Report; 2001. Available:

Dorian M, Ramírez GJ, López S, Hernández B. Acceptance and expressed emotion in Mexican American caregivers of relatives with schizophrenia. Fam Process. 2008;47:215–228.

Kirkwood B, Sterne J. Essential medical statistics 2nd Editio. (Blackwell Science); 2003.

Adewuya A, Ola B, Mosaku S, Fatoye F, Eegunranti A. Attitude towards antipsychotics among out-patients with schizophrenia in Nigeria. Acta Psychiatr. Scand. 2006;207–211.

Higashi K, Medic G, Littlewood KJ, Diez T, Granström O, Hert M. De. Medication adherence in schizophrenia: Factors influencing adherence and consequences of nonadherence, a systematic literature review. Ther Adv Psychopharmacol. 2013;3:200–18.

Stuart H, Arboleda-Flórez J. Community attitudes towards people with schizophrenia. Can. J. Psychiatry. 2001;46:245–52.

World Psychiatric Association Programme to reduce stigma and discrimination because of schizophrenia. Available:

Adelufosi A, Adebowale T, Abayomi O, Mosanya J. Medication adherence and quality of life among Nigerian outpatients with schizophrenia. Gen. Hosp. Psychiatry. 2012;72–79.

Matthias J, Wulf R. Attitude towards long acting depot antipsychotics: A Survey of patients, relatives and psychiatrist. Psychiatry Res. 2010;175:58–62.

Adelufosi AO, Ogunwale A, Adeponle AB, Abayomi O. Pattern of attendance and predictors of default among Nigerian outpatients with schizophrenia. Afr J Psychiatry. 2013;16:283–287.

Karthik MS, Kulhara PC. Attitude towards second-generation antipsychotics among patients with schizophrenia and their relatives. Hum. Psychopharmacol. Clin. Exp. 2013;28:457–465.

Kay S, Fiszbein A, Opler L. The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophr. Bull. 1987;13: 261–76.

Lawal R, Suleiman G, Onyeze B. Risperidone in the treatment of chronic schizophrenia. Niger. Med. Pract. 2003;44: 11–18.

Lasebikan VO, Ayinde OO. Family burden in caregivers of schizophrenia patients: Prevalence and socio-demographic correlates. Indian J. Psychol. Med. 2013;35:60–66.

Igberase O, Morankinyo O, Lawani A, James B, Omoaregba J. Burden of care among relatives of patients with schizophrenia in mid-western Nigeria. Int. J. Soc. Psychiatry. 2010;20:1–7.

Karthik M, Warikoo N, Chakrabarti S, Grover S, Kulhara P. Attitudes towards antipsychotics among patients with schizophrenia on first- or second-generation medications. Indian J. Psychol. Med. 2014;36:288–293.

Adebowale T, Oguunlesi A. Beliefs and knowledge about aetiology of mental illness among Nigerian psychiatric patients and their relatives. Afr J Med Sci. 1999;28: 35–41.

Schulze B, Angermeyer M. Subjective experiences of stigma. A focus group study of schizophrenic patients, their relatives and mental health professionals. Soc Sci Med. 2003;56:299–312.

Wolff G, Pathare S, Craig T, Leff J. Community attitudes to mental illness. Br J Psychiatry. 1996;168:183–90.

Freudenreich O, Cather C, Evins A, Henderson D, Goff D. Attitudes of schizophrenia outpatients toward psychiatric medications: Relationship to clinical variables and insight. J. Clin. Psychiatry. 2004;1372–1376.

Angermeyer M, Holzinger A, Matschinger H. Mental health literacy and attitude towards people with Psychiatry. Eur, Ment. Illn. a trend Anal. Based Popul. Surv. East. Part Ger. 2009;24:225–32.

Veltman A, Cameron J, Stewart D. The experience of providing care to relatives with chronic mental illness. J Nerv Ment Dis. 2002;190:108–14.