Movement Disorder Early in the Presentation of Two Children with Subacute Sclerosing Pan-Encephalitis

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Hanin Al-Gethami
Mohammad Talal Alrifai
Ahmed Al-Rumayyan
Waleed Al-Tuwaijri
Duaa Ba-Armah

Abstract

Subacute sclerosing panencephalitis (SSPE) is a progressive degenerative disease caused by measles infection with overall poor prognosis in spite multiple modalities of treatment. The course of the disease is characterized by progressive neurological decline in the form of behavioral and personality changes followed by a stage of characteristic periodic myoclonic spasms followed by a stage of quadriplegia movement disorder, vegetative state and frequently early death. Here we report two cases with atypical presentation of early rather than late movement disorder during illness and the unusual association of central precocious puberty preceding the course of illness in one of the cases.

Keywords:
Subacute sclerosing panencephalitis, prognosis, myoclonic spasms, quadriplegia movement disorder, central precocious puberty

Article Details

How to Cite
Al-Gethami, H., Alrifai, M., Al-Rumayyan, A., Al-Tuwaijri, W., & Ba-Armah, D. (2019). Movement Disorder Early in the Presentation of Two Children with Subacute Sclerosing Pan-Encephalitis. International Neuropsychiatric Disease Journal, 13(1), 1-10. https://doi.org/10.9734/indj/2019/v13i130101
Section
Case Study